Advanced Hematology Five-Part Differential

The VETSCAN HM5 is a fully-automated, five-part differential hematology analyzer displaying a comprehensive 22-parameter complete blood count (CBC) with cellular histograms on an easy-to-read touch-screen. Its superior performance, elegant design, ease of use, true database management capability, and minimal maintenance make it the optimal hematology system for veterinary clinics, research laboratories, and pharmaceutical and biotech companies.

Features & Benefits

Five-part differential on cat, dog, horse, cow, alpaca and llama; three-part on 11 other species

Flexibility to analyze 17 common species in your practice

22 parameters, including direct eosinophil counts and eosinophil percentage

Provides full CBCs analyses for even allergic and parasitic cases

Three to four minutes to results

Fast turnaround for each sample — run nearly 20 samples per hour in five-part mode

Small, space-saving, elegant design with large touch-screen display

Fits on nearly every clinic counter

Advanced, integrated self-cleaning system

Minimal maintenance facilitated by software reminders and step-by-step instructions

On-screen patient results trending

Easy patient monitoring over time

show all features and benefits

Reproducibility You Can Rely On

HM5 Reagent Pack


Reagent pack for HM5 hematology analyzer. Provides approximately 100 tests.


VETSCAN HM5 Demonstration

Simple Operation

Thumbnail Enter information.
Thumbnail Insert sample and press start.
Thumbnail Read results.
  • Height:

    36.5 cm (14 in)
  • Width:

    32 cm (12.5 in)
  • Depth:

    27 cm (10.6 in)



12 kg (26.5 lbs)

Power Requirements

100-240 volts AC, 50-60 Hz; or 12 volts DC

Reported Parameters

22 parameters including WBC, LYM, MON, NEU, BAS, EOS, LYM%, MON%, NEU%, EOS%, BAS%, RBC, HGB, HCT, MCV, MCH, MCHC, RDW, PLT, MPV, PCT, PDW

Sample Size

50-microliters (5-part diff.)
25-microliters (3-part diff.)


What technology does the VETSCAN HM5 utilize?

The VETSCAN HM5 uses a combination of chemical differentiation and impedance technology to provide the 5-part WBC differential. With impedance technology, electrically neutral blood cells generate an electrical pulse as they each pass through an electronically charged aperture. Cell counts are determined by the number of pulses measured in a given volume of blood over a set period of time. The size of the pulse generated is directly proportional to the volume of each cell. This size discrimination, along with susceptibility to various lysing agents, distinguishes the cell types and provides basis for the 5-part differential. The size of the VETSCAN HM5 aperture was specifically designed to accommodate veterinary blood cells, thereby providing optimal differentiation.

What type of sample is used?

Hematology analyses require EDTA-treated blood (from lavender or purple top tubes containing potassium EDTA only). It is important to ensure that your sample is well mixed and contains optimal proportions of blood and EDTA. The following guidelines should be followed: Fill each tube at least half-full with blood to eliminate dilution errors. Thoroughly mix each sample by gently inverting the filled potassium EDTA sample tube by hand 10 to 15 times to avoid clot formation. If possible, run the sample immediately after mixing. If testing is delayed and the sample is placed on a rocker, be sure to mix it thoroughly again before analysis by gently inverting the tube 10 to 15 times. This ensures the homogeneity of the sample. Do not shake samples. Doing so can damage the blood cells, and can form micro-bubbles that will cause inaccurate results. Never use a rocker for samples smaller than 1.0 ml. Rockers do not mix samples. Feline samples frequently demonstrate platelet aggregations (clumps). Vortex mixing for up to 10 seconds can disaggregate these clumps with no adverse effect on the sample. Some practitioners find that collecting blood from the medial saphenous vein using a vacutainer minimizes platelet clumping.

For further information on sample collection and handling, refer to our Tech Brief, "Sample Collection and Handling".

What species are supported?

Fifteen species are supported on the VETSCAN HM5. In 5-part differential mode: Dog, Cat, Horse, Cow, Alpaca and Llama. In the 3-part differential mode, currently validated species are: mouse, rabbit, rat, ferret, pig, goat, monkey, sheep and guinea pig.

What maintenance is recommended for the VETSCAN HM5?

As with any cell counter, the analyzer must be kept clean to avoid build up of debris and particle interference in the system. Performing the simple and easy preventative maintenance will keep the HM5 in optimal operating condition, thus ensuring peak performance, and high quality results.

What is the shelf-life of the VETSCAN HM5 hematology reagents?

Shelf life is 24 months from date of manufacture. Open reagent packs should be used within 26 weeks (~5 months).

What parameters are reported with the VETSCAN HM5?

22 parameters complete blood with cellular histograms are provided:


WBC: Total White Blood Cell Count Graphical WBC and EOS histograms provide added information about sample integrity and contents. 
LYM: lymphocytes and lymphocyte percentage 
MON: monocytes and monocyte percentage 
NEU: neutrophil and neutrophil percentage 
EOS: eosinophil and eosinophil percentage 
BAS: basophil and basophile percentage


HGB: Hemoglobin 
HCT: Hematocrit

RBC: Red Blood Cell count and indices: 
MCV: Mean Cell Volume 
MCH: Mean Corpuscular Hemoglobin 
MCHC: Mean Corpuscular Hemoglobin Concentration 
RDW: Red Cell Distribution Width 
Graphical RBC Histogram is included.


PLT: Platelet, or thrombocyte, count and parameters: 
MPV: Mean Platelet Volume 
PCT: Platelet hematocrit 
PDW: Platelet Distribution Width 
Graphical Platelet Histogram is included.

+ Show more questions